The General Crimes Section includes two units: the Felony Trial Unit and Misdemeanor Trial Unit. The General Crimes Section handles most of the cases prosecuted in D.C. Superior Court.

The Felony Trial Unit is responsible for the post-indictment prosecution of most felony cases brought in the Superior Court. The Section's attorneys handle a variety of cases involving trafficking, weapons offenses and stolen vehicles.

The Misdemeanor Trial Section prosecutes most Misdemeanor crimes in the District of Columbia, including offenses involving narcotics and weapons possession, theft, prostitution, animal cruelty, illegal dumping, destruction of property, threats and simple assault. The Section is divided into teams that typically include four attorneys, a paralegal and a legal assistant. Each team is assigned to one judge sitting on the Superior Court misdemeanor calendar. Members of the Section are in the court every day trying cases. The Section also administers various diversion programs.